• 产品编号:Asc-024
    • 产品名称:7-Chlorokynurenic acid
    • 产品规格:10mg/50mg
    • 价  格:840.00/2400.00
    • 供 应 商:Ascent
    • 库  存:
  • 7-Chlorokynurenic acid

    NMDA receptor glycine site antagonist (NMDA受体甘氨酸位点拮抗剂)
    Purity: >99%

    Biological Description
    Potent NMDA receptor glycine site antagonist. Water-soluble form available - please see 7-Chlorokynurenic acid sodium salt (#Asc-255).

    Useful References
    Kemp et al (1988) 7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proc.Natl.Acad.Sci. 85:6547 abstract

    Kleckner et al (1989) selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-methyl-D-aspartate receptors. Mol. Pharmacol. 36:430 abstract

    Moroni et al (1991)Thiokynurenates: a new group of antagonists of the glycine modulatory site of the NMDA receptor. Eur.J.Pharmacol. 199:227 abstract



    Chemical Information
    7-Chloro-4-hydroxyquinoline-2-carboxylic acid
     


     

    • Desiccate at +4°C
    • MW 223.62
    • Soluble to 100 mM in water with 1 eq NaOH, Soluble in DMSO to 100mM
    • C10H6ClNO3
    • 18000-24-3