• 产品编号:Asc-052
    • 产品名称:NMDA/天门冬氨酸
    • 产品规格:50mg/100mg/500mg
    • 价  格:900.00/1620.00/3720.00
    • 供 应 商:Ascent
    • 库  存:
  • NMDA

    Excitotoxic amino acid
    Purity: >98%

    Biological Description
    Excitotoxic amino acid. Prototypic agonist at the ionotropic NMDA glutamate receptor which is involved in long-term potentiation, ischemia, and epilepsy. Also available in Low-Cost Kit: Ionotropic agonists (Asc-323).

    Useful References
    Hansen et al (1990). Structural, conformational, and stereochemical requirements of central excitatory amino acid receptors. Med.Res.Rev. 10: 55-94

    Kew et al (2005) Ionotropic and metabotropic glutamate receptor structure and pharmacology. Psychopharmacol. 179:4-29 abstract

    Collingridge et al (1989) Excitatory amino acid receptors in the vertebrate central nervous system. Pharmacol. Rev. 41:143-210



    Our products in action...
    Feligioni et al. (2009) Protein SUMOylation modulates calcium influx and glutamate release from presynaptic terminals. EJN 29: 1348-1356 abstract

     


    Chemical Information
    (R)-2-(Methylamino)succinic acid
     


     

    • Desiccate at +4°C
    • MW 147.13
    • Soluble to 100 mM in water
    • C5H9NO4
    • 6384-92-5