• 产品编号:Asc-128
    • 产品名称:CGP 39551/级丙烯 39551
    • 产品规格:10mg/50mg
    • 价  格:1620.00/6570.00
    • 供 应 商:Ascent
    • 库  存:
  • CGP 39551

    Competitive NMDA antagonist (竞争的NMDA拮抗剂)
    Purity: >99%

    Biological Description
    Competitive NMDA receptor antagonist (Ki = 310 nM for displacement of CPP binding in rat brain). Potent oral anticonvulsant activity in vivo.

    Useful References
    Fagg et al (1990) CGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-aspartate receptor antagonists with oral activity. Br J Pharmacol. 99:791-7 abstract

    Schmutz et al (1990) The competitive NMDA receptor antagonists CGP 37849 and CGP 39551 are potent, orally-active anticonvulsants in rodents. Naunyn Schmiedebergs Arch Pharmacol. 342(1):61-6. abstract

    Fagg et al (1990) CGP 37849 and CGP 39551: novel competitive N-methyl-D-aspartate receptor antagonists with potent oral anticonvulsant activity. Prog Clin Biol Res. 361:421-7



    Chemical Information
    (E)-4-(ethoxycarbonyl)-4-amino-2-methylbut-2-enylphosphonic acid
     

    • Desiccate at +4°C
    • MW 237.19
    • Soluble in water to 100 mM (with warming)
    • C8H16NO5P
    • 127910-32-1