• 产品编号:Asc-004
    • 产品名称:DL-AP5
    • 产品规格:10mg/50mg
    • 价  格:611.00/2775.00
    • 供 应 商:Ascent
    • 库  存:
  • DL-AP5

     NMDA glutamate site antagonist (NMDA谷氨酸盐位点拮抗剂)
    Purity: >99%

    Biological Description
    Competitive NMDA receptor glutamate site antagonist. Water-soluble form available - please see DL-AP5 sodium salt (#Asc-271).

    Useful References
    Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75:65.

    Davies and Watkins (1982) Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235:378.

    Watkins and Evans (1981) Excitatory amino acid transmitters. Ann. Rev. Pharmacol. Toxicol. 21:165



    Our products in action...
    Oren et al. (2009) Role of ionotropic glutamate receptors in long-term potentiation in rat hippocampal CA1 oriens-lacunosum moleculare interneurons. J Neurosci 29(4):939-950 abstract

    Urbanski et al. (2009) Depolarizing GABAergic synaptic input triggers endocannabinoid-mediated retrograde synaptic signaling. Synapse. 63(8):643-52. abstract


    Chemical Information
    DL-(-)-2-Amino-5-phosphonopentanoic acid
     


     

    • Desiccate at +4°C
    • MW 197.13
    • Soluble to 25 mM in water and to 100 mM in 1eq. NaOH
    • C5H12NO5P
    • 76326-31-3

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