• 产品编号:Asc-003
    • 产品名称:D-AP5
    • 产品规格:1mg/10mg/50mg/100mg
    • 价  格:500.00/1388.00/6161.00/8381.00
    • 供 应 商:Ascent
    • 库  存:
  • D-AP5

    NMDA glutamate site antagonist (NMDA谷氨酸盐位点拮抗剂)
    Purity: >99%

    Biological Description
    Competitive NMDA receptor glutamate site antagonist. More active form of DL-AP5.

    Useful References
    Kew and Kemp (2005) Ionotropic and metabotropic glutamate receptor structure and pharmacology. Psychopharmacol. 179:4

    Evans et al (1982) The effect of a series of ω-phosphonic-α-carboxylic amino acids on electrically evoked and amino acid induced responses in isolated spinal cord preparations. Br.J.Pharmacol. 75:65.

    Davies and Watkins (1982) Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235:378



    Our products in action...
    Bardoni et al. (2007) BDNF-mediated modulation of GABA and glycine release in dorsal horn lamina II from postnatal rats. Dev Neurobiol. 67:960-75. abstract

    Trigo et al. (2007) Enhancement of GABA release through endogenous activation of axonal GABA(A) receptors in juvenile cerebellum. J Neurosci. 27:12452-63. abstract


    Chemical Information
    D-(-)-2-Amino-5-phosphonopentanoic acid
     
     

     

    • Desiccate at +4°C
    • MW 197.13
    • Soluble to 100 mM in water
    • C5H12NO5P
    • 79055-68-8


     

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