• 产品编号:Asc-578
    • 产品名称:(R,S)-Sulpiride
    • 产品规格:100mg
    • 价  格:600.00
    • 供 应 商:Ascent
    • 库  存:
  • (R,S)-Sulpiride             D2-like dopamine receptor antagonist

    Biological Description

    D2-like dopamine receptor antagonist. Shows anti-psychotic activity.

    Useful References

    Van der Niepen et al (1991) Hypotensive and regional hemodynamic effects of the dopamine receptor agonist SK & F 85174 in the anesthetized rat. Arch Int Pharmacodyn Ther. 313:98-107. abstract

    Seeman et al (1993) Dopamine D4 receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective. Eur J Pharmacol. 233:173-4. abstract

    Seeman et al (1994) Dopamine receptor pharmacology. Trends Pharmacol Sci. 15:264-70. abstract

     

    Chemical Information

    (R,S)-(±)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide

    Asc-578 (<em>R,S</em>)-Sulpiride
    • Store at +4°C
    • MW 341.42
    • Soluble in DMSO to 100 mM and in 1eq. HCl to 50 mM
    • C15H23N3O4S
    • 15676-16-1