• 产品编号:Asc-573
    • 产品名称:L-DOPA/左旋多巴
    • 产品规格:5g/25g/100g
    • 价  格:600.00/2190.00/7020.00
    • 供 应 商:Ascent
    • 库  存:
  • L-DOPA              Dopamine precursor     

    Other names: Levodopa

    Purity: >99%

     

    Biological Description

    Dopamine precursor. Blood brain barrier permeable. Increases dopamine levels in Parkinsons disease models to display anti-Parkinsons disease properties.

    Useful References

    Pisani et al (2009) Levodopa-induced dyskinesia and striatal signaling pathways. Proc Natl Acad Sci U S A. 106:2973-4. abstract

    Munoz (2008) Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of L-DOPA-induced dyskinesia. Brain. 131:3380-94. abstract

    Ahmed et al (2010) Lentiviral overexpression of GRK6 alleviates L-dopa-induced dyskinesia in experimental Parkinsons disease. Sci Transl Med. 2(28):28ra28 abstract

     

    Chemical Information

    L-3,4-Dihydroxyphenylalanine

    Asc-573 L-DOPA
    • Desiccate at -20°C
    • MW 197.19
    • Soluble in water to 5 mM and in 1eq. HCl to 100 mM
    • C9H11NO4
    • 59-92-7

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