• 产品编号:PRO-1059
    • 产品名称:重组人外切体成分5/EXOSC5 Human
    • 产品规格:5ug/25ug/1mg
    • 价  格:700.00/1800.00/
    • 供 应 商:ProSpecbio
    • 库  存:
  • Catalogue Number PRO-1059
    Synonyms Exosome component 5, Chronic myelogenous leukemia tumor antigen 28, Ribosomal RNA-processing protein 46, exosome complex exonuclease RRP46, RRP41B, hRrp46p, CML28, p12B.

     

    Introduction EXOSC5 is a member of the RNase PH family. EXOSC5 is known to cooperate with Exosome component 8 and Exosome component 1. EXOSC5 is a Non-catalytic component of the RNA exosome complex and has 3->5 exoribonuclease activity. EXOSC5 take part in a large number of cellular RNA processing and degradation events. EXOSC5 is expressed in a large range of hematopoietic and epithelial tumor cell lines, but not in standard hematopoietic tissues or other standard tissue, with the exception of testis.
    Description EXOSC5 Human Recombinant produced in E. coli is a single polypeptide chain containing 256 amino acids (1-235) and having a molecular mass of 27.5kDa.
    EXOSC5 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
    Source E.coli.
    Physical Appearance Sterile Filtered colorless solution.
    Formulation The EXOSC5 solution (0.5mg/1ml) contains PBS buffer (pH 7.4), 200mM Nacl, 2mM DTT and 30% glycerol.
    Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

    Avoid multiple freeze-thaw cycles.
    Purity Greater than 90% as determined by SDS-PAGE.
    Amino acid sequence MGSSHHHHHH SSGLVPRGSH MMEEETHTDA KIRAENGTGS SPRGPGCSLR HFACEQNLLS RPDGSASFLQ GDTSVLAGVY GPAEVKVSKE IFNKATLEVI LRPKIGLPGV AEKSRERLIR NTCEAVVLGT LHPRTSITVV LQVVSDAGSL LACCLNAACM ALVDAGVPMR ALFCGVACAL DSDGTLVLDP TSKQEKEARA VLTFALDSVE RKLLMSSTKG LYSDTELQQC LAAAQAASQH VFRFYRESLQ RRYSKS
    Usage ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.