CATALOG: E10724
PRESENTATION: 1ml affinity purified rabbit polyclonal antibody at 200µg/ml in 10mM
PBS, pH 7.4 with BSA and Sodium Azide.
IMMUNOGEN: Synthetic peptide corresponding to C-terminal of human claudin 12.
SPECIES REACTIVITY: Human. Others-not known.
DESCRIPTION: The claudin superfamily consists of many structurally related proteins
in humans. These proteins, which include claudin 1 through 18, are
important structural and functional components of tight junctions in
paracellular transport. Claudins are located in both epithelial and
endothelial cells in all tight junction-bearing tissues. Claudins, which
consist of four trans-membrane domains and two extracellular loops,
make up tight junction strands.
APPLICATION AND SUGGESTED DILUTIONS:
• Western blotting (Ab at 1-2µg/ml for 2hrs at RT)
MOLECULAR WEIGHT: 26kDa
POSITIVE CONTROL: Rat brain
CELLULAR LOCALIZATION: Cytoplasmic (with occasional staining of macrophage lysozymes)
STORAGE & STABILITY: Ab with sodium azide is stable for 24 months when stored at 2-80C.
LEGAL CONSIDERATION: This product is recommended FOR RESEARCH USE ONLY.
