| Catalogue Number | ANT-228 |
| Type | Mouse Antibody Monoclonal. |
| Introduction | p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma. |
| Clone | PP53SHG. |
| Description | Monoclonal antibodies are produced by immunizing mouse with full length His-tagged p53 protein. |
| Ig Subclass | Mouse IgG2a. |
| Formulation | 1×PBS & 50% glycerol. |
| Stability / Shelf Life | 2 years at -20°C. 1 month at 4°C. |
| Dilution | Western Blotting: 2μg/ml. |
| Applications | Western Blot, Immunoprecipitation. |
| Usage | ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
