| CAS Number | 67-03-8 |
|---|---|
| Molecular Formula | C12H17ClN4OS · HCl |
| Molecular Weight | 337.27 g/mol |
| Solubility | Ethanol: 10 mg/mL Ethanol (95%): 3 mg/mL Glycerol: Freely soluble Water: Freely Soluble |
| Melting Point | 248 °C (dec.) |
| Flash Point | 100 °C |
| Storage Conditions | 2-8 °C |
Thiamine is a member of the B vitamins (B1) and is commonly used in cell culture media. Thiamine is freely soluble in water (500 mg/mL) and glycerol, and slightly soluble in ethanol (10 mg/mL).
Thiamine is involved in the synthesis of neurotransmitters acetylcholine and gamma-aminobutyric acid (GABA) in mammalian cells. In addition, thiamine serves as a precursor for thiamine pyrophosphate (TPP), a coenzyme involved in amino acid and carbohydrate synthesis.
Because of its active role in normal cell processes, thiamine HCl is commonly used as a cell culture supplement.
