• 产品编号:T016
    • 产品名称:Tetracycline, EP/四环素, EP
    • 产品规格:5g/25g/100g
    • 价  格:询价
    • 供 应 商:美国TOKU-E
    • 库  存:
  • CAS Number 60-54-8
    Molecular Formula C22H24N2O8 · xH2O
    Molecular Weight 444.43 g/mol (anhydrous basis)
    Form Powder
    Appearance White powder
    Storage Conditions -20 °C

    Description
    Tetracycline is a bacteriostatic polyketide antibiotic frequently used in a wide range of in vitro cell culture applications.  TOKU-E offers three forms of tetrcycline: tetracycline HCL (T004), tetracycline, USP (T051), and tetracycline, EP (T016).  Tetracycline, USP and tetracycline, EP are sparingly soluble in aqueous solution at 0.231 mg/mL.  Tetracycline HCl, is slighly soluble in aqueous solution at 10mg/mL.
    Mechanism
    Tetracycline inhibits protein synthesis by preventing amino-acyl tRNA from binding to the “A” site in the bacterial ribosome.
    Spectrum
    Tetracycline is a broad spectrum antibiotic targeting a wide range of gram positive and gram negative bacteria responsible for upper respiratory tract infections.
    • Microbiology Applications
      Tetracycline is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram positive and gram negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients. Representative MIC values include:
      • Haemophilus influenzae 6.3 µg/mL – 12.5 µg/mL
      • Streptococcus pneumoniae 2 µg/mL - 8 µg/mL
      • For a complete list of tetracycline MIC values, click here.
    • Plant Biology Applications
      Tetracycline has shown to suppress aster yellows disease symptoms on China Aster and Chrysanthemum plants. Multiple applications of tetracycline resulted in symptomless plant growth.
    • Mammalian Biology Applications
      Tetracycline is routinely used to select for cells containing resistance plasmids in cell lines such as HeLa at an effective concentration of 1µg/mL. For additional information on your cell culture needs, please visit our cell-culture database.